ChemoCentryx Initiates Clinical Trial of CCX168, A Novel Small Molecule C5aR Antagonist for the Treatment of Inflammatory and Autoimmune Diseases

MOUNTAIN VIEW, Calif., Jan. 28 /PRNewswire/ -- ChemoCentryx, Inc., today announced the initiation of a Phase I clinical trial of CCX168, an orally-administered small molecule designed to treat autoimmune diseases.  CCX168 is a highly potent and very selective compound that specifically...

Cancer, Heart Disease, Stroke, Diabetes, Chronic Pain and Depression Share a Major Pathology Factor

For humans, sunlight and vitamin D is critically important for the development, growth, and maintenance of a healthy body, from birth until death. "Humans make thousands of units of vitamin D within minutes of whole body exposure to sunlight. From what we know of nature, it is unlikely such a system evolved by chance," states Dr. John Cannell, Executive Director, Vitamin D Council. According to the Vitamin D Council, current research has implicated sunlight and vitamin D deficiency as a major...

Graves’ eye disease: Immune cell linked to inflammation and scarring identified

A cell type that causes significant scarring in lung disease appears to have a similar effect in Graves' disease, researchers have found. The cells, called fibrocytes, are present at a higher than normal frequency in patients with Graves' disease, according to a new study, the first to associate fibrocytes with this autoimmune...