CK-1

Body-clock drug offers breakthrough approach to depression

Scientists in the U.K. say that a CK-1 inhibitor in Pfizer's pipeline was able to reset the body clock in mice, a discovery that has profound implications for developing a new class of drugs that could address everything from jet lag to mental illnesses like depression and bipolar disorder. "We've discovered that we can control one of the key molecules involved in setting the speed at which the clock ticks and in doing so we can actually kick it into a new rhythm," Manchester University's...
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