299423: GSK cites progress with a new-gen antibiotic

Investigators at GlaxoSmithKline are excited about the prospect of a new antibiotic that uses a different approach to kill drug-resistant bacteria now rampaging through hospitals. Imaging technology has captured proof that the antibiotic latches on to the enzyme topoisomerase, which bacteria need to replicate. A generation of quinolones has effectively targeted that enzyme. But they're losing effectiveness and GSK, teamed with the Wellcome Trust's Seeding Drug Discovery initiative and the U.S....