After testing the IPO waters with a plan to sell shares for $12 to $14, San Diego-based Trius Therapeutics found investors in a frigid mood for a biotech with no products and no revenue. Trius ended up pricing its long delayed IPO at $5 a share, netting $45 million and change for its ongoing R&D work.
Trius has been engaged in developing new antibiotics, a lively field in drug development. But the markets have demonstrated little appetite for biotechs still focused entirely on the high...